Abstract Background: Recently, exportin gene family members have been demonstrated to play essential roles in tumor progression. However, research on…
Abstract Background: A substantial proportion of patients with metastatic clear cell renal cell carcinoma (ccRCC) cannot derive benefit from immune…
Abstract Lens epithelium-derived growth factor (LEDGF/p75) is a reader of epigenetic marks and a potential target for therapeutic intervention. Its…
Abstract Background: The six‐transmembrane epithelial antigen of the prostate 3 (STEAP3) is a metalloreductase, which is essential for iron uptake.…
Abstract Human sterile α motif and HD domain-containing protein 1 (SAMHD1) has deoxyribonucleoside triphosphohydrolase (dNTPase) activity that allows it to…
Abstract Background: Triggering receptors expressed by myeloid cells-1 (TREM1) is a receptor belonging to the immunoglobulin superfamily and plays an…
Abstract Transporter associated with antigen processing 1(TAP1) serves as a protein to transport antigenic peptides from the surface of the…
Abstract Ferredoxin 1 (FDX1), an iron-sulphur protein, is responsible for electron transfer in a range of metabolic redox reactions. Clear…
Abstract Background: Prolyl 4-hydroxylase subunit alpha 1 (P4HA1) provides the majority of the catalytic site of the active P4H enzyme.…
Abstract Purpose: Clear cell renal cell carcinoma (ccRCC) is one of the most common diseases in the world, with high…