Concurrent loss of the Y chromosome in cancer and T cells impacts outcome
Abstract Loss of the Y chromosome (LOY) in peripheral blood mononuclear cells (PBMCs) is the most common somatic alteration in…
Chromosomes
Cannabinoid exposure as a major driver of pediatric acute lymphoid Leukaemia rates across the USA: combined geospatial, multiple imputation and causal inference study
Abstract Background: Acute lymphoid leukaemia (ALL) is the commonest childhood cancer whose incidence is rising in many nations. In the…
CdbA is a DNA-binding protein and c-di-GMP receptor important for nucleoid organization and segregation in Myxococcus xanthus
Abstract Cyclic di-GMP (c-di-GMP) is a second messenger that modulates multiple responses to environmental and cellular signals in bacteria. Here…
Pan-cancer repository of validated natural and cryptic mRNA splicing mutations
Abstract We present a major public resource of mRNA splicing mutations validated according to multiple lines of evidence of abnormal…