Cannabinoid-Driven Rewiring of GPCR and Ion Channel Signaling in Lung Cancer
Abstract Lung cancer remains the leading cause of cancer-related mortality worldwide, with non-small cell lung cancer accounting for the majority…
chemotherapy resistance
Targeting carbohydrate metabolism in colorectal cancer – synergy between DNA-damaging agents, cannabinoids, and intermittent serum starvation
Abstract Chemotherapy is a therapy of choice for many cancers. However, it is often inefficient for long-term patient survival and…
Cannabinoids and triple-negative breast cancer treatment
Abstract Triple-negative breast cancer (TNBC) accounts for about 10-20% of all breast cancer cases and is associated with an unfavorable…
The potential neuroprotective effects of cannabinoids against paclitaxel-induced peripheral neuropathy: in vitro study on neurite outgrowth
Abstract Introduction: Chemotherapy-induced peripheral neuropathy (CIPN) is a shared burden for 68.1% of oncological patients undergoing chemotherapy with Paclitaxel (PTX).…
Molecular Mechanism of Autophagy and Its Regulation by Cannabinoids in Cancer
Abstract Simple Summary: This review examines the complex function of autophagy in malignancy and explores its regulation by cannabinoids in…
Transient Receptor Potential Cation Channels in Cancer Therapy
Abstract In mammals, the transient receptor potential (TRP) channels family consists of six different families, namely TRPC (canonical), TRPV (vanilloid),…