A History of Drug Discovery for Treatment of Nausea and Vomiting and the Implications for Future Research
Abstract The origins of the major classes of current anti-emetics are examined. Serendipity is a recurrent theme in discovery of…
Abstract The origins of the major classes of current anti-emetics are examined. Serendipity is a recurrent theme in discovery of…
Abstract Purpose: Oral cannabinoids (i.e., dronabinol, nabilone) containing the active component of marijuana, delta(Δ)9-tetrahydrocannabinol (THC), are available for the treatment…
Abstract Background: The objective was to evaluate the cost-effectiveness of NEPA, an oral fixed combination netupitant (NETU, 300 mg) and…
Abstract Despite the advent of classic anti-emetics, chemotherapy-induced nausea is still problematic, with vomiting being somewhat better managed in the…
Abstract Chemotherapy-induced nausea and vomiting (CINV) is one of the most common symptoms feared by patients, but may be prevented…
Abstract Introduction: Cannabis is the most common illegal substance used in the world. The psychoactive nature of cannabis is primarily…
Abstract Prevention of chemotherapy-induced nausea and vomiting (CINV) is a key component of treatment for patients with cancer. Guidelines are…
Abstract Cannabis use has become one of the most commonly abused drugs in the world. It is estimated that each…