75 years of forensic profiling: A critical review
Abstract The interest in characterization of drugs abused started in 1948 with the aim of determining the origin of opium.…
Chemical attribution signatures (CAS)
Identification of a Novel Cuproptosis-Related Gene Signature and Integrative Analyses in Thyroid Cancer
Abstract Cuproptosis is a novel programmed cell death that depends on copper. The role and potential mechanism of cuproptosis-related genes…
Identification and validation of a novel senescence-related biomarker for thyroid cancer to predict the prognosis and immunotherapy
Abstract Introduction: Cellular senescence is a hallmark of tumors and has potential for cancer therapy. Cellular senescence of tumor cells…
A novel necroptosis-related gene signature associated with immune landscape for predicting the prognosis of papillary thyroid cancer
Abstract Background: Necroptosis, a type of programmed cell death, has been implicated in a variety of cancer-related biological processes. However,…
Development and validation of a cancer-associated fibroblast-derived lncRNA signature for predicting clinical outcomes in colorectal cancer
Abstract Cancer-associated fibroblasts (CAFs) are actively involved in cancer progression through generating extracellular matrix and orchestrating the crosstalk within the…
RB1 and TP53 co-mutations correlate strongly with genomic biomarkers of response to immunity checkpoint inhibitors in urothelial bladder cancer
Abstract Background: Muscle invasive urothelial bladder carcinoma (MIBC) present RB1 and TP53 somatic alterations in a variable percentage of tumors…
Identification of a Recurrence Signature and Validation of Cell Infiltration Level of Thyroid Cancer Microenvironment
Abstract Though many patients with thyroid cancer may be indolent, there are still about 50% lymph node metastases and 20%…
Identifying hub genes of papillary thyroid carcinoma in the TCGA and GEO database using bioinformatics analysis
Abstract Background: Thyroid carcinoma (THCA) is a common endocrine malignant tumor. Papillary carcinoma with low degree of malignancy and good…
Pan-cancer analysis identifies telomerase-associated signatures and cancer subtypes
Abstract Background: Cancer cells become immortalized through telomere maintenance mechanisms, such as telomerase reverse transcriptase (TERT) activation. In addition to…