Abstract Background: Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest and most treatment-resistant cancers, with limited progress in improving…
Abstract Mounting evidence demonstrates that cannabinoids have anti-cancer properties. The mechanism by which the cannabinoids induce cell death is still…
Abstract Pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive malignancies with a median 5 year-survival rate of 12%.…
Abstract Background: Cannabigerol (CBG), a non-psychotropic phytocannabinoid found in Cannabis sativa plants, has been the focus of recent studies due…
Abstract Gliomas are highly aggressive cancer types that are in urgent need of novel drugs and targeted therapies. Treatment protocols…
Abstract Available data suggest that cannabidiol (CBD) may ameliorate symptoms of insulin resistance by modulating the sphingolipid concentrations in particular…
Abstract Numerous studies showed that sustained obesity results in accumulation of bioactive lipid derivatives in several tissues, including skeletal muscle,…
Abstract Anandamide is a lipid neurotransmitter derived from arachidonic acid, a polyunsaturated fatty acid. The chemical differences between anandamide and…
Abstract The role of cannabinoids in thrombosis remains controversial. In view of the primary importance of tissue factor (TF) in…