Abstract (1) Background: The psychoactive and non-psychoactive constituents of cannabis, Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD), synergistically reduce allodynia in various…
Abstract Background: Chronic neuropathic pain (NP) presents therapeutic challenges. Interest in the use of cannabis-based medications has outpaced the knowledge…
Abstract Products derived from the plant Cannabis sativa are widely appreciated for their analgesic properties and are employed for the…
Abstract There is no clear understanding of the mechanisms causing persistent pain in patients with whiplash associated disorder (WAD). The…
Abstract Systems pharmacology employs computational and mathematical methods to study the network of interactions a drug may have within complex…
Abstract Objective: To compare the effectiveness, safety, and tolerability of add-on nabiximols (NBX) oromucosal spray vs typical oral long-acting opioid…
Abstract In this review, a timeline starting at the willow bark and ending in the latest discoveries of analgesic and…
Abstract Until recently, glia were considered to be a structural support for neurons, however further investigations showed that glial cells…
Abstract Human immunodeficiency virus (HIV) infection and antiretroviral therapy can independently induce HIV-associated neuropathic pain (HIV-NP). There is a dearth…
Abstract Background: Legalization of cannabis encourages the development of specific cultivars to treat disease such as neuropathic pain. Because of…