Abstract The excitatory neurotransmitter glutamate has been implicated in experience-dependent neuroplasticity and drug-seeking behaviors. Type 5 metabotropic glutamate (mGlu5) receptors…
Abstract Cannabis abuse during adolescence confers an increased risk for developing later in life cognitive deficits reminiscent of those observed…
Abstract Long-term cannabis users manifest deficits in dopaminergic functions, reflecting Δ9-tetrahydrocannabinol (THC)-induced neuroadaptive dysfunctional dopamine signaling, similar to those observed…
Abstract Cannabis use is rising, yet there is poor understanding of biological processes that might link chronic cannabis use to…
Abstract The neurobiological mechanisms underlying the association between cannabis use and acute or long-lasting psychosis are not completely understood. While…
Abstract Recent years have seen increased interest in psychopathologies related to trauma exposure. Specifically, there has been a growing awareness…
Abstract Neuronal circuits within the prefrontal cortex (PFC) mediate higher cognitive functions and emotional regulation that are disrupted in psychiatric…
Abstract Drug addiction affects a large extent of young people and disadvantaged populations. Drugs of abuse impede brain circuits or…
Abstract Cannabinoids (Δ9-tetrahydrocannabinol) are the active ingredient of marijuana (cannabis) which is the most commonly abused illicit drug in the…