Abstract Background: Evidence suggests that the endocannabinoid system (ECS) is crucial for regulating inflammation, cell proliferation and pain. The ECS…
Abstract Background: MicroRNAs (miRNAs) are epigenetic regulators of T cell maturation and exhaustion. However, the mechanisms by which miRNAs influence…
Abstract Background: The incidence of papillary thyroid cancer (PTC) continues to rise all over the world, 10–15% of the patients…
Abstract Lymphotoxin beta receptor (LTBR) is a positive T cell proliferation regulator gene. It is closely associated with the tumor…
Abstract Background: Little is known on how metabolic reprogramming potentially prompts transition of activated and resting CD4+ memory T cells…
Abstract Simple Summary: Immunotherapy targeting immune checkpoints and stromal cells in the tumor microenvironment is currently one of the most…
Abstract CD93 is a transmembrane receptor that is mainly expressed on endothelial cells. A recent study found that upregulated CD93…
Abstract Aneuploidy is a chromosomal abnormality associated with poor prognosis in many cancer types. Here, we tested the hypothesis that…
Abstract Background: Recent evidences had shown that loss in phosphatase and tensin homolog deleted on chromosome 10 (PTEN) was associated…
Abstract Medical marijuana is increasingly prescribed as an analgesic for a growing number of indications, amongst which terminal cancer and…