Effects of Rare Phytocannabinoids on the Endocannabinoid System of Human Keratinocytes
Abstract The decriminalization and legalization of cannabis has paved the way for investigations into the potential of the use of…
cannabis-derived phytocannabinoids
Amino Acid Supplementation as a Biostimulant in Medical Cannabis (Cannabis sativa L.) Plant Nutrition
Abstract There is growing evidence to support the involvement of nutrients and biostimulants in plant secondary metabolism. Therefore, this study…
Cannabis sativa Extract Induces Apoptosis in Human Pancreatic 3D Cancer Models: Importance of Major Antioxidant Molecules Present Therein
Abstract In recent years, interest in Cannabis sativa L. has been rising, as legislation is moving in the right direction.…
THC and CBD Fingerprinting of an Elite Cannabis Collection from Iran: Quantifying Diversity to Underpin Future Cannabis Breeding
Abstract Cannabis (Cannabis sativa L.) has a rich history of human use, and the therapeutic importance of compounds produced by…
The Neuroprotective Effects of Cannabis-Derived Phytocannabinoids and Resveratrol in Parkinson’s Disease: A Systematic Literature Review of Pre-Clinical Studies
Abstract Currently, there are no pharmacological treatments able to reverse nigral degeneration in Parkinson’s disease (PD), hence the unmet need…
Pharmacokinetics of cannabichromene in a medical cannabis product also containing cannabidiol and Δ9-tetrahydrocannabinol: a pilot study
Abstract Purpose: Cannabichromene (CBC) is a phytocannabinoid commonly found in cannabis, yet its acute post-dose pharmacokinetics (PK) have not been…
Targeting of Protein’s Messenger RNA for Viral Replication, Assembly and Release in SARS-CoV-2 Using Whole Genomic Data From South Africa: Therapeutic Potentials of Cannabis Sativa L
Abstract The possible evolutionary trend of COVID-19 in South Africa was investigated by comparing the genome of SARS-CoV-2 isolated from…
Detrimental Effect of Cannabidiol on the Early Onset of Diabetic Nephropathy in Male Mice
Abstract Anti-inflammatory and antidiabetogenic properties have been ascribed to cannabidiol (CBD). CBD-based medicinal drugs have been approved for over a…
Sex differences in medical cannabis-related adverse effects
Abstract Supplemental Digital Content is Available in the Text. Women are more susceptible to medical cannabis–related adverse effects because of…
Neuroprotective and Symptomatic Effects of Cannabidiol in an Animal Model of Parkinson’s Disease
Abstract Parkinson’s disease (PD) is a neurodegenerative disorder characterized by the loss of dopaminergic neurons in the Substantia Nigra pars…