Use of Natural Compounds in the Management of Diabetic Peripheral Neuropathy
Abstract Nephropathy, retinopathy cardiomyopathy and peripheral neuropathy are all recognized as important complications in about 50% of diabetes mellitus (DM)…
cannabinoids
Cannabis Extract Treatment for Terminal Acute Lymphoblastic Leukemia with a Philadelphia Chromosome Mutation
Abstract Acute lymphoblastic leukemia (ALL) is a cancer of the white blood cells and is typically well treated with combination…
Cannabinoids: Well-Suited Candidates for the Treatment of Perinatal Brain Injury
Abstract Perinatal brain injury can be induced by a number of different damaging events occurring during or shortly after birth,…
Involvement of PPARγ in the antitumoral action of cannabinoids on hepatocellular carcinoma
Abstract Cannabinoids exert antiproliferative effects in a wide range of tumoral cells, including hepatocellular carcinoma (HCC) cells. In this study,…
Nabilone for the treatment of medication overuse headache: results of a preliminary double-blind, active-controlled, randomized trial
Abstract Medication overuse headache (MOH) is a severe burden to sufferers and its treatment has few evidence-based indications. The aim…
A placebo-controlled study to assess Standardized Field Sobriety Tests performance during alcohol and cannabis intoxication in heavy cannabis users and accuracy of point of collection testing devices for detecting THC in oral fluid
Abstract Rationale: Standardized Field Sobriety Tests (SFST) and oral fluid devices are used to screen for driving impairment and roadside…
The role of cannabinoids in prostate cancer: Basic science perspective and potential clinical applications
Abstract Prostate cancer is a global public health problem, and it is the most common cancer in American men and…
The Role of Cannabinoids in Modulating Emotional and Non-Emotional Memory Processes in the Hippocampus
Abstract Cannabinoid agonists generally have a disruptive effect on memory, learning, and operant behavior that is considered to be hippocampus-dependent.…
Endocannabinoid system in cardiovascular disorders – new pharmacotherapeutic opportunities
Abstract The long history of Cannabis sativa had its development stimulated and oriented for medicine after the discovery and chemical…
Mechanisms of Broad-Spectrum Antiemetic Efficacy of Cannabinoids against Chemotherapy-Induced Acute and Delayed Vomiting
Abstract Chemotherapy-induced nausea and vomiting (CINV) is a complex pathophysiological condition and consists of two phases. The conventional CINV neurotransmitter…