Genomic and Chemical Diversity of Commercially Available High-CBD Industrial Hemp Accessions
Abstract High consumer demand for cannabidiol (CBD) has made high-CBD hemp (Cannabis sativa) an extremely high-value crop. However, high demand…
cannabinoids
Cannabinoquinones: Synthesis and Biological Profile
Abstract Neutral cannabinoids are oxidatively unstable and are converted into quinone derivatives by atmospheric- and/or chemical oxidative dearomatization. The study…
UHPLC-MS/MS Analysis of Cannabidiol and Its Metabolites in Serum of Patients with Resistant Epilepsy Treated with CBD Formulations
Abstract Cannabidiol (CBD) is a promising therapeutic agent with analgesic, myorelaxant, and anti-epileptic actions. Recently, a purified form of CBD…
Confound, Cause, or Cure: The Effect of Cannabinoids on HIV-Associated Neurological Sequelae
Abstract The persistence of human immunodeficiency virus-1 (HIV)-associated neurocognitive disorders (HAND) in the era of effective antiretroviral therapy suggests that…
Influence of Technological Maturity on the Secondary Metabolites of Hemp Concentrate (Cannabis sativa L.)
Abstract During the last decade, the popularity of hemp products has been rising rapidly. Products containing cannabidiol (CBD) are of…
Potential and Limits of Cannabinoids in Alzheimer’s Disease Therapy
Abstract Simple Summary: This review was aimed at exploring the potentiality of drugging the endocannabinoid system as a therapeutic option…
A Quantitative 1H NMR Method for Screening Cannabinoids in CBD Oils
Abstract Toxicologically relevant levels of the psychoactive ∆9-tetrahydocannabinol (∆9-THC) as well as high levels of non-psychoactive cannabinoids potentially occur in…
Cannabinoids and Inflammations of the Gut-Lung-Skin Barrier
Abstract Recent studies have identified great similarities and interferences between the epithelial layers of the digestive tract, the airways and…
Cannabis Use and Car Crashes: A Review
Abstract In this review, state-of-the-art evidence on the relationship between cannabis use, traffic crash risks, and driving safety were analyzed.…
Can Cannabidiol Affect the Efficacy of Chemotherapy and Epigenetic Treatments in Cancer?
Abstract The success of cannabinoids with chronic neuropathic pain and anxiety has been demonstrated in a multitude of studies. With…