Cannabinol: History, Syntheses, and Biological Profile of the Greatest “Minor” Cannabinoid
Abstract Cannabis (Cannabis sativa L.) is an outstanding source of bioactive natural products, with more than 150 different phytocannabinoids isolated…
cannabinoids
Effects of cannabinoids on ligand-gated ion channels
Abstract Phytocannabinoids such as Δ9-tetrahydrocannabinol and cannabidiol, endocannabinoids such as N-arachidonoylethanolamine (anandamide) and 2-arachidonoylglycerol, and synthetic cannabinoids such as CP47,497…
Intracellular Molecular Targets and Signaling Pathways Involved in Antioxidative and Neuroprotective Effects of Cannabinoids in Neurodegenerative Conditions
Abstract In the last few decades, endocannabinoids, plant-derived cannabinoids and synthetic cannabinoids have received growing interest as treatment options in…
Cannabidiol in Dentistry: A Scoping Review
Abstract Cannabidiol (CBD) has been gaining increased attention in contemporary society but seems to have been little explored in dentistry.…
The impact of phyto- and endo-cannabinoids on central nervous system diseases：A review
Abstract Background and aim: Cannabis sativa L. is a medicinal plant with a long history. Phyto-cannabinoids are a class of…
Antitumorigenic Effect of Cannabidiol in Lung Cancer: What Do We Know So Far?–A Mini Review
Abstract Lung cancer remains a major factor contributing to morbidity and mortality worldwide. CBD and THC could serve as a…
The Therapeutic Potential of the Endocannabinoid System in Age-Related Diseases
Abstract The endocannabinoid system (ECS) dynamically regulates many aspects of mammalian physiology. ECS has gained substantial interest since growing evidence…
El papel de los cannabinoides en los trastornos del neurodesarrollo de niños y adolescentes
Abstract Introducción.: Los trastornos del neurodesarrollo tienen una etiología multifactorial que resulta de la interacción entre factores biológicos y ambientales.…
Cannabinoids for behavioral symptoms in severe dementia: Safety and feasibility in a long-term pilot observational study in nineteen patients
Abstract Context: The management of behavioral symptoms and rigidity in patients with dementia constitutes a significant challenge. Short-term studies suggest…
Semi-quantitative analysis of cannabinoids in hemp (Cannabis sativa L.) using gas chromatography coupled to mass spectrometry
Abstract Background: Hemp (Cannabis sativa L.) is a producer of cannabinoids. These organic compounds are of increasing interest due to…