Can Hemp Help? Low-THC Cannabis and Non-THC Cannabinoids for the Treatment of Cancer
Abstract Cannabis has been used to relieve the symptoms of disease for thousands of years. However, social and political biases…
Cannabinoid receptors
Terpenoids, Cannabimimetic Ligands, beyond the Cannabis Plant
Abstract Medicinal use of Cannabis sativa L. has an extensive history and it was essential in the discovery of phytocannabinoids,…
Cannabinoids and Hormone Receptor-Positive Breast Cancer Treatment
Abstract Breast cancer (BC) is the most common cancer in women worldwide. Approximately 70–80% of BCs express estrogen receptors (ER),…
Absence of Entourage: Terpenoids Commonly Found in Cannabis sativa Do Not Modulate the Functional Activity of Δ9-THC at Human CB1 and CB2 Receptors
Abstract Introduction: Compounds present in Cannabis sativa such as phytocannabinoids and terpenoids may act in concert to elicit therapeutic effects.…
Modulation of the Endocannabinoid System as a Potential Anticancer Strategy
Abstract Currently, the involvement of the endocannabinoid system in cancer development and possible options for a cancer-regressive effect of cannabinoids…
Future Aspects for Cannabinoids in Breast Cancer Therapy
Abstract Cannabinoids (CBs) from Cannabis sativa provide relief for tumor-associated symptoms (including nausea, anorexia, and neuropathic pain) in the palliative…
Potential Mechanisms Underlying the Deleterious Effects of Synthetic Cannabinoids Found in Spice/K2 Products
Abstract The chief psychoactive constituent of many bioactive phytocannabinoids (Δ9-tetrahydrocannabinol, Δ9-THC) found in hemp, cannabis or marijuana plants are scientifically…
Traditional Uses of Cannabinoids and New Perspectives in the Treatment of Multiple Sclerosis
Abstract Recent findings highlight the emerging role of the endocannabinoid system in the control of symptoms and disease progression in…
Cannabinoids in Glioblastoma Therapy: New Applications for Old Drugs
Abstract Glioblastoma (GBM) is the most malignant brain tumor and one of the deadliest types of solid cancer overall. Despite…
Pharmacotherapeutic considerations for use of cannabinoids to relieve pain in patients with malignant diseases
Abstract Purpose: The aim of this review was to assess the efficacy of cannabis preparations for relieving pain in patients…