cannabinoid receptor partial agonist

September 2, 2022

Structure–Activity Relationship Development Efforts towards Peripherally Selective Analogs of the Cannabinoid Receptor Partial Agonist BAY 59-3074

Abstract Selective modulation of peripheral cannabinoid receptors (CBRs) has potential therapeutic applications in medical conditions, including obesity, diabetes, liver diseases,…

January 17, 2022

Quantifying the Kinetics of Signaling and Arrestin Recruitment by Nervous System G-Protein Coupled Receptors

Abstract Neurons integrate inputs over different time and space scales. Fast excitatory synapses at boutons (ms and μm), and slow…

June 10, 2020

Disentangling the effects of cannabis and cigarette smoking on impulsivity

Abstract Background: Cannabis smoking and cigarette smoking often co-occur, yet limited research has investigated the potentially different role impulsivity may…

May 13, 2015

4′-O-methylhonokiol increases levels of 2-arachidonoyl glycerol in mouse brain via selective inhibition of its COX-2-mediated oxygenation

Abstract Background and purpose: 4′-O-methylhonokiol (MH) is a natural product showing anti-inflammatory, anti-osteoclastogenic, and neuroprotective effects. MH was reported to…