Epigenetic Effects of Drugs of Abuse
Abstract Drug addiction affects a large extent of young people and disadvantaged populations. Drugs of abuse impede brain circuits or…
cannabinoid (CBD)
Recent advances in the endocrinology of the sebaceous gland
Abstract The sebaceous gland, long considered an evolutionary relic with little-to-no physiological relevance in humans, has emerged in recent decades…
Cannabinoids Modulate Neuronal Activity and Cancer by CB1 and CB2 Receptor-Independent Mechanisms
Abstract Cannabinoids include the active constituents of Cannabis or are molecules that mimic the structure and/or function of these Cannabis-derived…
Modulation of Astrocyte Activity by Cannabidiol, a Nonpsychoactive Cannabinoid
Abstract The astrocytes have gained in recent decades an enormous interest as a potential target for neurotherapies, due to their…
Endocannabinoids: A Promising Impact for Traumatic Brain Injury
Abstract The endogenous cannabinoid (endocannabinoid) system regulates a diverse array of physiological processes and unsurprisingly possesses considerable potential targets for…
The CB2 receptor and its role as a regulator of inflammation
Abstract The CB2 receptor is the peripheral receptor for cannabinoids. It is mainly expressed in immune tissues, highlighting the possibility…
Cellular Mechanisms of Action of Drug Abuse on Olfactory Neurons
Abstract Cannabinoids (Δ9-tetrahydrocannabinol) are the active ingredient of marijuana (cannabis) which is the most commonly abused illicit drug in the…
Critical appraisal of the potential use of cannabinoids in cancer management
Abstract Cannabinoids have been attracting a great deal of interest as potential anticancer agents. Originally derived from the plant Cannabis…
A role for O-1602 and G protein-coupled receptor GPR55 in the control of colonic motility in mice
Abstract Objective: The G protein-coupled receptor 55 (GPR55) is a novel cannabinoid (CB) receptor, whose role in the gastrointestinal (GI)…
Sexually Dimorphic Effects of Cannabinoid Compounds on Emotion and Cognition
Abstract This review addresses the issue of sex differences in the response to cannabinoid compounds focusing mainly on behaviors belonging…