The role of cannabis in epilepsy illustrated by two case reports
Abstract Cannabis use may increase seizure frequency and severity, complicating management. Cannabis may reduce effectiveness of antiseizure medication and neurostimulation.…
cannabinoid (CBD)
Synaptic signatures of perinatal cannabinoids: A systematic review of rodent hippocampal synaptic plasticity, learning, and memory
Abstract The expanding legalization of cannabis raises significant public health concerns about its use during pregnancy, particularly due to the…
Differential metabolic pathways underlie THC- and CBD-mediated inhibition of B-cell activation in both young and aged mice
Abstract Objective: B lymphocytes play a crucial role in immunity but also contribute to the pathogenesis of various diseases. Cannabis…
Biosynthesis of novel cannabigerolic acid derivatives by engineering the substrate specificity of aromatic prenyltransferase
Abstract Introduction: Cannabinoids possess significant therapeutic potential, but their natural chemical diversity derived from plant biosynthesis is limited. Efficient biotransformation…
Postharvest Drying and Curing Affect Cannabinoid Contents and Microbial Levels in Industrial Hemp (Cannabis sativa L.)
Abstract Postharvest operations affect the yield and quality of industrial hemp (Cannabis sativa L.). This study aimed to investigate the…
Enhancing Cannabinoid Bioavailability in Pain Management: The Role of Cyclodextrins
Abstract Chronic pain (CP), including pain related to cancer, affects approximately 2 billion people worldwide, significantly diminishing quality of life…
Determination of Cannabinoids in Meat Products and Animal Feeds in Singapore Using Liquid Chromatography–Tandem Mass Spectrometry
Abstract There has been a growing interest in the use of hemp as an animal feed ingredient considering its economic…
Chemotherapy-Induced Peripheral Neuropathy: A Recent Update on Pathophysiology and Treatment
Abstract Chemotherapy-induced peripheral neuropathy (CIPN) is a major long-lasting side effect of some chemotherapy drugs, which threatens cancer survival rate.…
From Chronic Cannabis to Cyclic Chaos: A Glimpse Into Cannabinoid Hyperemesis Syndrome
Abstract Cannabinoid hyperemesis syndrome (CHS) pathophysiology remains largely unknown, and it is often misdiagnosed. This paper identifies the clinical causes…
Influence of Fungicide Application on Rhizosphere Microbiota Structure and Microbial Secreted Enzymes in Diverse Cannabinoid-Rich Hemp Cultivars
Abstract Microbes and enzymes play essential roles in soil and plant rhizosphere ecosystem functioning. However, fungicides and plant root secretions…