Shape Matters: Plant Architecture Affects Chemical Uniformity in Large-Size Medical Cannabis Plants
Abstract Since plant organs sense their environment locally, gradients of micro-climates in the plant shoot may induce spatial variability in…
cannabigerol (CBG)
Protective Effects of Cannabidivarin and Cannabigerol on Cells of the Blood–Brain Barrier Under Ischemic Conditions
Abstract Background and Objectives: Preclinical studies have shown cannabidiol is protective in models of ischemic stroke. Based on results from…
Anti-Bacterial Properties of Cannabigerol Toward Streptococcus mutans
Abstract Streptococcus mutans (S. mutans) is a gram-positive facultatively anaerobic bacterium and the most common pathogen associated with tooth caries.…
Efficacy of Phytocannabinoids in Epilepsy Treatment: Novel Approaches and Recent Advances
Abstract Epilepsy is a neurological disorder mainly characterised by recurrent seizures that affect the entire population diagnosed with the condition.…
A geospatiotemporal and causal inference epidemiological exploration of substance and cannabinoid exposure as drivers of rising US pediatric cancer rates
Abstract Background: Age-adjusted US total pediatric cancer incidence rates (TPCIR) rose 49% 1975–2015 for unknown reasons. Prenatal cannabis exposure has…
Cannabigerol Is a Potential Therapeutic Agent in a Novel Combined Therapy for Glioblastoma
Abstract Simple Summary: Among primary brain tumours, glioblastoma is the most aggressive. As early relapses are unavoidable despite standard-of-care treatment,…
SNP in Potentially Defunct Tetrahydrocannabinolic Acid Synthase Is a Marker for Cannabigerolic Acid Dominance in Cannabis sativa L.
Abstract The regulation of cannabinoid synthesis in Cannabis sativa is of increasing research interest as restrictions around the globe loosen…
Phytocannabinoid‐dependent mTORC1 regulation is dependent upon inositol polyphosphate multikinase activity
Abstract Background and Purpose: Cannabidiol (CBD) has been shown to differentially regulate the mechanistic target of rapamycin complex 1 (mTORC1)…
Biotechnological Approaches on Two High CBD and CBG Cannabis sativa L. (Cannabaceae) Varieties: In Vitro Regeneration and Phytochemical Consistency Evaluation of Micropropagated Plants Using Quantitative 1H-NMR
Abstract High cannabidiol (CBD) and cannabigerol (CBG) varieties of Cannabis sativa L., a species with medicinal properties, were regenerated in…
Contemporary epidemiology of rising atrial septal defect trends across USA 1991–2016: a combined ecological geospatiotemporal and causal inferential study
Abstract Background: Cardiovascular anomalies are the largest group of congenital anomalies and the major cause of death in young children,…