Whole proteome mapping of compound-protein interactions
Abstract Off-target binding is one of the primary causes of toxic side effects of drugs in clinical development, resulting in…
cannabigerol (CBG)
Fabrication and Preliminary In Vitro Evaluation of 3D-Printed Alginate Films with Cannabidiol (CBD) and Cannabigerol (CBG) Nanoparticles for Potential Wound-Healing Applications
Abstract In this study, drug carrier nanoparticles comprised of Pluronic-F127 and cannabidiol (CBD) or cannabigerol (CBG) were developed, and their…
An Examination of the Anti-Cancer Properties of Plant Cannabinoids in Preclinical Models of Mesothelioma
Abstract Simple Summary: Mesothelioma is a deadly disease with few treatment options. Phytocannabinoids derived from the cannabis plant are garnering…
The Origin and Biomedical Relevance of Cannabigerol
Abstract The constant search for new pharmacologically active compounds, especially those that do not exhibit toxic effects, intensifies the interest…
Impact of converging sociocultural and substance-related trends on US autism rates: combined geospatiotemporal and causal inferential analysis
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s00406-022-01446-0. Article type: Research Article Keywords: Cannabis, Cannabinoid, Δ9-tetrahydrocannabinol,…
Cannabidiol and Cannabigerol Inhibit Cholangiocarcinoma Growth In Vitro via Divergent Cell Death Pathways
Abstract Cholangiocarcinoma (CCA) is a rare and highly lethal disease with few effective treatment options. Cannabinoids, cannabidiol (CBD) and cannabigerol…
Medical Cannabis Activity Against Inflammation: Active Compounds and Modes of Action
Abstract Inflammation often develops from acute, chronic, or auto-inflammatory disorders that can lead to compromised organ function. Cannabis (Cannabis sativa)…
Direct Quantitation of Phytocannabinoids by One-Dimensional 1H qNMR and Two-Dimensional 1H-1H COSY qNMR in Complex Natural Mixtures
Abstract The widespread use of phytocannabinoids or cannabis extracts as ingredients in numerous types of products, in combination with the…
Cannabigerol Effect on Streptococcus mutans Biofilms—A Computational Approach to Confocal Image Analysis
Abstract Biofilms are complex bacterial structures in which bacterial cells thrive as a community. Many bacterial species, including pathogens, form…
Geotemporospatial and causal inferential epidemiological overview and survey of USA cannabis, cannabidiol and cannabinoid genotoxicity expressed in cancer incidence 2003–2017: part 2 – categorical bivariate analysis and attributable fractions
Abstract Background: As the cannabis-cancer relationship remains an important open question epidemiological investigation is warranted to calculate key metrics including…