Abstract Introduction: Cannabidiol (CBD) has shown potential therapeutic benefits in veterinary medicine, but further investigations are needed to establish its…
Abstract Purpose: The oral bioavailability of cannabinoids is limited due to extensive first-pass metabolism, reducing their therapeutic efficacy. This study…
Abstract This study evaluated the comparative plasma pharmacokinetics of two oral CBD formulations—oil-based (5 mg/kg) and treat-mixed (50 mg)—in dogs…
Abstract Introduction: This study investigated the pharmacokinetics, safety, and tolerability of a full-spectrum CBD-dominant oil formulated in medium-chain triglycerides (MCT…
Abstract The semi-synthetic cannabinoid hexahydrocannabinol (HHC) has become a highly discussed topic in forensic toxicology since 2022 due to its…
Abstract Background/Objectives: This study aims to develop a solid self-nanoemulsifying drug delivery system (SNEDDS) to enhance the solubility and oral…
Abstract Pain management in horses plays a pivotal role in the therapeutic approach to several diseases. Horses have cannabinoid receptors…
Abstract Drug interactions are major causes of interindividual variability in tacrolimus exposure and effect. Tacrolimus, a widely used drug in…
Abstract Prenatal cannabis use is associated with neurodevelopmental deficits, likely due to exposure to the psychoactive cannabinoid, (-)-Δ9-tetrahydrocannabinol, and its…
Abstract The legalization of cannabis in several states across the US has increased the need to better understand its effects…