Plasma biomarkers in neuropsychiatric syndromes: A narrative review
Abstract Neuropsychiatric symptoms (NPS) are common features of neurodegenerative disease (NDD) but are relatively understudied compared to cognition, especially regarding…
Cannabidiol derivative/ NRF2/ BACH1/ HMOX1/ neurodegenerative diseases
Tetrahydrocurcumin Ameliorates Cerebral Ischemia–Reperfusion Injury and Restores Blood–Brain Barrier Dysfunction by Inhibiting Ferroptosis
Abstract Background: Cerebral ischemia–reperfusion (I/R) injury is a major consequence of ischemic stroke, leading to blood–brain barrier (BBB) disruption, neuroinflammation,…
The microbiota–gut–brain axis in mental and neurodegenerative disorders: opportunities for prevention and intervention
Abstract The microbiota–gut–brain axis (MGBA) is increasingly recognized as a critical regulator of brain health, influencing both neurodevelopment and age-related…
Plant-Derived Nutraceuticals in Mental Health and Brain Function: Mechanisms of Action and Therapeutic Potential
Abstract Considering the multiple benefits of nutraceuticals, and given the growing interest in exploring these effects, understanding their mechanisms and…
Advancing Brain Health Naturally: β-Caryophyllene and Xanthohumol as Neuroprotective Agents
Abstract Neurodegenerative diseases (NDDs) represent a class of incurable and progressive disorders characterized by the gradual degeneration of the structure…
Management and Prevention of Neurodegenerative Disorders: Can Antioxidant-Rich Dietary Interventions Help?
Abstract Neurodegenerative diseases are associated with the senescence of functional neurons, which hampers brain functions. These diseases are caused by…
Tau PET Imaging With [18 F]MK‐6240: Limited Affinity for Primary Tauopathies and High Specificity for Alzheimer’s Disease
Abstract Introduction: Second‐generation tau‐PET tracers like [18F]MK‐6240 are increasingly used both for diagnosing and quantifying Alzheimer’s Disease (AD) tauopathy. However,…
The Multifaceted Roles of BACH1 in Disease: Implications for Biological Functions and Therapeutic Applications
Abstract BTB domain and CNC homolog 1 (BACH1) belongs to the family of basic leucine zipper proteins and is expressed…
Plant Secondary Metabolites as Modulators of Mitochondrial Health: An Overview of Their Anti-Oxidant, Anti-Apoptotic, and Mitophagic Mechanisms
Abstract Plant secondary metabolites (PSMs) are a diverse group of bioactive compounds, including flavonoids, polyphenols, saponins, and terpenoids, which have…
Cannabidiol Alleviates Intestinal Fibrosis in Mice with Ulcerative Colitis by Regulating Transforming Growth Factor Signaling Pathway
Abstract Objective: The aim of this study is to investigate the protective effect of Cannabidiol (CBD) on DSS-induced colitis in…