Influence of Technological Maturity on the Secondary Metabolites of Hemp Concentrate (Cannabis sativa L.)
Abstract During the last decade, the popularity of hemp products has been rising rapidly. Products containing cannabidiol (CBD) are of…
Cannabidiol (CBD)
Potential and Limits of Cannabinoids in Alzheimer’s Disease Therapy
Abstract Simple Summary: This review was aimed at exploring the potentiality of drugging the endocannabinoid system as a therapeutic option…
A Quantitative 1H NMR Method for Screening Cannabinoids in CBD Oils
Abstract Toxicologically relevant levels of the psychoactive ∆9-tetrahydocannabinol (∆9-THC) as well as high levels of non-psychoactive cannabinoids potentially occur in…
Epileptic Phenotype and Cannabidiol Efficacy in a Williams–Beuren Syndrome Patient With Atypical Deletion: A Case Report
Abstract Epilepsy is a rare clinical manifestation in Williams–Beuren syndrome patients. However, some studies report the presence of infantile spasms…
The Heat Sensing Trpv1 Receptor Is Not a Viable Anticonvulsant Drug Target in the Scn1a +/− Mouse Model of Dravet Syndrome
Abstract Cannabidiol has been approved for the treatment of drug-resistant childhood epilepsies including Dravet syndrome (DS). Although the mechanism of…
Repurposing Cannabidiol as a Potential Drug Candidate for Anti-Tumor Therapies
Abstract In recent years, evidence has accumulated that cannabinoids—especially the non-psychoactive compound, cannabidiol (CBD)—possess promising medical and pharmacological activities that…
Efficacy of Phytocannabinoids in Epilepsy Treatment: Novel Approaches and Recent Advances
Abstract Epilepsy is a neurological disorder mainly characterised by recurrent seizures that affect the entire population diagnosed with the condition.…
Evaluating cannabidiol (CBD) expectancy effects on acute stress and anxiety in healthy adults: a randomized crossover study
Abstract Rationale: Cannabidiol (CBD) has been reported to attenuate stress and anxiety, but little is known about the extent to…
Duration of Neurocognitive Impairment With Medical Cannabis Use: A Scoping Review
Abstract While the recreational use of cannabis has well-established dose-dependent effects on neurocognitive and psychomotor functioning, there is little consensus…
Cannabidiol in Pharmacoresistant Epilepsy: Clinical Pharmacokinetic Data From an Expanded Access Program
Abstract Background and Aim: Data on the clinical pharmacokinetics of cannabidiol (CBD) are scanty. We explored the effect of demographic…