Protective Effects of Cannabidiol on the Membrane Proteome of UVB-Irradiated Keratinocytes
Abstract Ultraviolet (UV) radiation contained in sunlight disturbs the redox state of skin cells, leading to changes in the structures…
Cannabidiol/ BACH1/ HMOX1/ NRF2/ Keratinocytes
The Differential Effect of Cannabidiol on the Composition and Physicochemical Properties of Keratinocyte and Fibroblast Membranes from Psoriatic Patients and Healthy People
Abstract The development of psoriasis is accompanied by oxidative stress, which can modify the components of skin cells. Therefore, the…
The Effect of Cannabidiol on UV-Induced Changes in Intracellular Signaling of 3D-Cultured Skin Keratinocytes
Abstract Human epidermal keratinocytes are constantly exposed to UV radiation. As a result, there is a significant need for safe…
Cannabidiol-Mediated Changes to the Phospholipid Profile of UVB-Irradiated Keratinocytes from Psoriatic Patients
Abstract UVB phototherapy is treatment for psoriasis, which increases phospholipid oxidative modifications in the cell membrane of the skin. Therefore,…
Cannabidiol induces antioxidant pathways in keratinocytes by targeting BACH1
Abstract Cannabidiol (CBD) is a major non-psychotropic phytocannabinoid that attracted a great attention for its therapeutic potential against different pathologies…
Effects of JWH015 in cytokine secretion in primary human keratinocytes and fibroblasts and its suitability for topical/transdermal delivery
Abstract Background: JWH015 is a cannabinoid (CB) receptor type 2 agonist that produces immunomodulatory effects. Since skin cells play a…