Comprehensive Landscape of RRM2 with Immune Infiltration in Pan-Cancer
Abstract Simple Summary: RRM2 is a crucial subunit of ribonucleotide reductase. In this article, we provided a comprehensive analysis of…
Cancer prognosis
Thrombospondin-2 acts as a bridge between tumor extracellular matrix and immune infiltration in pancreatic and stomach adenocarcinomas: an integrative pan-cancer analysis
Abstract Background: Thrombospondin-2 (THBS2) is a versatile glycoprotein that regulates numerous biological functions, including the apoptosis-proliferation balance in endothelial cells,…
Characterizing HDAC Pathway Copy Number Variation in Pan-Cancer
Abstract Background: Histone deacetylase (HDAC) plays a crucial role in regulating the expression and activity of a variety of genes…
The Prognostic and Immunotherapeutic Significance of AHSA1 in Pan-Cancer, and Its Relationship With the Proliferation and Metastasis of Hepatocellular Carcinoma
Abstract The AHSA1 is a main activator of ATPase of Hsp90. Hsp90 is involved in various metabolic and developmental processes…
A Systematic Analysis Reveals the Prognostic and Immunological Role of Reptin/RUVBL2 in Human Tumors
Abstract Reptin/RUVBL2 is involved in the remodeling of chromatin, DNA damage repair, and regulation of the cell cycle, all of…
Prognostic Significance and Immunological Role of FBXO5 in Human Cancers: A Systematic Pan-Cancer Analysis
Abstract F-box protein 5 (FBXO5), an essential subunit of the ubiquitin protein ligase complex, is increasingly recognized to exhibit important…
Comprehensive Analysis of the Expression and Prognosis for MCM4 in Uterine Corpus Endometrial Carcinoma
Abstract Background: Mini chromosome maintenance protein 4 (MCM4) belongs to the family of mini chromosome maintenance proteins (MCMs) that plays…
Identification and Validation of a Prognostic Signature for Thyroid Cancer Based on Ferroptosis-Related Genes
Abstract Background: Thyroid cancer is the most common endocrine malignancy. Most PTC patients have a good prognosis; however, there are…
SQLE, A Key Enzyme in Cholesterol Metabolism, Correlates With Tumor Immune Infiltration and Immunotherapy Outcome of Pancreatic Adenocarcinoma
Abstract Background: Pancreatic adenocarcinoma (PAAD) is a treatment-refractory cancer with poor prognosis. Accumulating evidence suggests that squalene epoxidase (SQLE) plays…
Identification of the Putative Tumor Suppressor Characteristics of FAM107A via Pan-Cancer Analysis
Abstract Family with sequence similarity 107, member A(FAM107A) was supposed as a tumor suppressor for various types of tumors. However,…