ITGAV as a promising diagnostic, immunological, and prognostic biomarker in pan-cancer
Abstract Integrin αV (ITGAV) plays a key role in cell adhesion, migration, and immune regulation, and is implicated in tumor…
Cancer prognosis
Machine learning derived development and validation of extracellular matrix related signature for predicting prognosis in adolescents and young adults glioma
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-13547-6. Article type: Research Article Keywords: Adolescents and young…
RAB5B: explore its carcinogenic potential and understand its role, prognostic value and biological significance in pan-cancer
Abstract Background: The RAB5B protein belongs to the RAB family and is primarily localized to early endosomes. It regulates the…
Analysis of the prognostic and immune role of MCM6 in pan-cancer and experimental validation in lung adenocarcinoma cells
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-13598-9. Article type: Research Article Keywords: MCM6, Pan-cancer, Prognosis,…
Pan-cancer analysis reveals SGO1 as a potential cancer prognostic and immunological biomarker
Abstract Shugoshin 1 (SGO1) is primarily known for its critical functions in chromosome segregation during cell division, protecting cohesin complexes…
Phosphoglycerate kinase 1 as a potential prognostic biomarker in papillary thyroid carcinoma
Abstract Backgroud: Papillary thyroid carcinoma (PTC) represents a malignant epithelial tumor characterized with a preference for younger individuals. Despite its…
Exploring the potential value of SRC in pan cancer based on bioinformatics methods
Abstract Background: Tyrosine-Protein Kinase Src (SRC), a non-receptor tyrosine kinase encoded by the Src gene, plays a crucial role in…
NSUN6 expression correlates with prognosis and immune infiltration in human cancers based on pan-cancer analysis
Abstract NSUN6 is a regulator of tRNA methylation that partially exists in the Golgi and centrosomes. It catalyzes the methylation…
Pan-cancer analysis of oncogenic role of MAGOH and experiment validation in hepatocellular carcinoma
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-08678-9. Article type: Research Article Keywords: MAGOH (Mago-nashi homolog),…
Interplay of disulfidptosis and the tumor microenvironment across cancers: implications for prognosis and therapeutic responses
Abstract Supplementary Information: The online version contains supplementary material available at 10.1186/s12885-025-14246-1. Article type: Research Article Keywords: Pan-cancer, Disulfidptosis, Prognosis,…