Pan-cancer analysis of FBXW family with potential implications in prognosis and immune infiltration
Abstract Background: The F-box and WD repeat domain containing (FBXW) family of SCF E3 complexes has 10 members that are…
Cancer prognosis
MYCBP2 expression correlated with inflammatory cell infiltration and prognosis immunotherapy in thyroid cancer patients
Abstract Introduction: Immune checkpoint inhibitors (ICIs) have shown promising results for the treatment of multiple cancers. ICIs and related therapies…
Systematic Investigation of the Multifaceted Role of SOX11 in Cancer
Abstract Simple Summary: The transcription factor SOX11 is a member of the SRY box-containing family. Recently, SOX11 research has shifted…
Pan‐cancer analyses reveal molecular and clinical characteristics of cuproptosis regulators
Abstract Imbalance in copper homeostasis can be lethal. A recent study found that excess copper induces cell death in a…
Exploring the Characteristics of Monkeypox-Related Genes in Pan-Cancer
Abstract Monkeypox, an infectious virus that is a member of the Poxviridae family, has raised great threats to humans. Compared…
Identification of GINS1 as a therapeutic target in the cancer patients infected with COVID-19: a bioinformatics and system biology approach
Abstract Background: Coronavirus disease 2019 (COVID-19) caused a series of biological changes in cancer patients which have rendered the original…
Pan-Cancer analysis shows that ACO2 is a potential prognostic and immunotherapeutic biomarker for multiple cancer types including hepatocellular carcinoma
Abstract Background: Recent evidence increasingly suggests key roles for the tricarboxylic acid cycle and fatty acid metabolism in tumor progression…
A pan-cancer analysis of the oncogenic role of ribonucleotide reductase subunit M2 in human tumors
Abstract Background: Recent studies have identified ribonucleotide reductase subunit M2 (RRM2) as a putative promoter of tumors. However, no systematic…
Comprehensive analysis of the expression profile and clinical implications of regulator of chromosome condensation 2 in pan-cancers
Abstract The Regulator of Chromosome Condensation 2 (RCC2) is an important gene that regulates mitosis and cytoplasmic division in the…
Immunological role and prognostic value of SPARCL1 in pan-cancer analysis
Abstract Background: Secreted protein acidic and rich in cysteine-like 1 (SPARCL1) was a kind of extracellular matrix glycoprotein. SPARCL1 was…