Pan cancer characterization of genes whose expression has been associated with LINE-1 antisense promoter activity
Abstract Background: Long interspersed nuclear element-1 (LINE-1 or L1) comprises 17% of the human genome. As the only autonomous and…
Cancer prognosis
Comprehensive analysis of the oncogenic and immunological role of SPON2 in human tumors
Abstract Background: Sapiens spondin-2 (SPON2) is a protein found in the extracellular matrix that plays a role in a number…
SERPINB7 as a prognostic biomarker in cervical cancer: Association with immune infiltration and facilitation of the malignant phenotype
Abstract Purpose: The purpose of this study was to investigate the expression patterns, predictive significance, and roles in the immune…
Development of a thyroid cancer prognostic model based on the mitophagy-associated differentially expressed genes
Abstract Background: The prevalence of thyroid cancer (ThyC), a frequent malignant tumor of the endocrine system, has been rapidly increasing…
Prognostic model of kidney renal clear cell carcinoma using aging-related long noncoding RNA signatures identifies THBS1-IT1 as a potential prognostic biomarker for multiple cancers
Abstract Aging is responsible for the main intrinsic triggers of cancers; however, the studies of aging risk factors in cancer…
Prognostic value and immunological role of CSNK1D in human cancers
Abstract CSNK1D, also known as CK1δ, is a crucial gene involved in various biological processes such as cell cycle, transcriptional…
Estimating disease-free survival of thyroid cancer based on novel cuprotosis-related gene model
Abstract Background: Cuprotosis is a newly discovered form of cell death that differs from other types of cell death. The…
Pan-cancer analysis identified OAS1 as a potential prognostic biomarker for multiple tumor types
Abstract Background: 2’,5’-oligoadenylate synthetase 1 (OAS1), has been reported as a tumor driver gene in breast carcinoma and pancreatic carcinoma.…
Nuclear mitochondria-related genes-based molecular classification and prognostic signature reveal immune landscape, somatic mutation, and prognosis for glioma
Abstract Background: Glioma is the most frequent malignant primary brain tumor, and mitochondria may influence the progression of glioma. The…
Comprehensive analysis and experimental validation reveal elevated CLCN4 is a promising biomarker in endometrial cancer
Abstract Several studies have reported the role of CLCN4 in tumor progression. However, its mechanism remains to be thoroughly studied.…