A comprehensive analysis of the prognostic and immunological role of ANK3 in pan-cancer
Abstract Background: Cancer is a common cause of death around the world. Immunotherapy plays a significant role in cancer treatment…
Cancer prognosis
Preliminary exploration of the potential biological functions and prognosis values of RAB4B in pan-cancer combing with experimental validation in BLCA
Abstract Background: Ras-related protein Rab-4B (RAB4B), a small GTPase in the RAS superfamily, is involved in glucose homeostasis, synaptic homeostasis,…
Comprehensive analysis of the effects of the cuprotosis-associated gene SLC31A1 on patient prognosis and tumor microenvironment in human cancer
Abstract Background: Solute carrier family 31 (copper transporter), member 1 (SLC31A1) is a key factor in maintaining intracellular copper concentration…
MMP12 is a Potential Predictive and Prognostic Biomarker of Various Cancers Including Lung Adenocarcinoma
Abstract Objective: This study sought to explore the clinical value of matrix metalloproteinases 12 (MMP12) in multiple cancers, including lung…
Prognostic Significance of KIF-12 Functioning as a Tumour Suppressor in Papillary Thyroid Carcinoma
Abstract Objective: To explore the potential value of a novel marker, KIF-12, in the progression and prognosis of papillary thyroid…
PCDH8 is a novel prognostic biomarker in thyroid cancer and promotes cell proliferation and viability
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s10142-024-01312-3. Article type: Research Article Keywords: PCDH8, Thyroid cancer,…
Comprehensive analysis of the protein phosphatase 2A regulatory subunit B56ε in pan-cancer and its role and mechanism in hepatocellular carcinoma
Abstract BACKGROUND: B56ε is a regulatory subunit of the serine/threonine protein phosphatase 2A, which is abnormally expressed in tumors and…
Pan-cancer analysis reveals potential immunological and prognostic roles of METTL7A in human cancers
Abstract Methyltransferase-like protein 7A (METTL7A) is an m6A RNA methyltransferase that has been linked to cancer prognosis and drug resistance.…
Investigating the clinical role and prognostic value of genes related to insulin-like growth factor signaling pathway in thyroid cancer
Abstract Background: Thyroid cancer (THCA) is the most common endocrine malignancy having a female predominance. The insulin-like growth factor (IGF)…
Integrative analysis confirms TPX2 as a novel biomarker for clinical implication, tumor microenvironment, and immunotherapy response across human solid tumors
Abstract Targeting Protein for Xenopus Kinesin Like Protein 2 (TPX2) serves as a microtubule associated protein for the regulation of…