NEK2 is a potential pan-cancer biomarker and immunotherapy target
Abstract Background: NEK2 is a member of the NEKs family and plays an important role in cell mitosis. Increasing evidence…
Cancer prognosis
Comprehensive Pan-Cancer Analysis of the Prognostic Role of KLF Transcription Factor 2 (KLF2) in Human Tumors
Abstract Background: KLF2 is a transcription factor expressed early in mammalian development that plays a role in many processes of…
Deep contrastive learning for predicting cancer prognosis using gene expression values
Abstract Recent advancements in image classification have demonstrated that contrastive learning (CL) can aid in further learning tasks by acquiring…
IPCEF1: Expression Patterns, Clinical Correlates and New Target of Papillary Thyroid Carcinoma
Abstract Introduction: Despite the generally favorable prognosis of PTC (Papillary Thyroid Carcinoma), it can still exhibit aggressive behavior and lead…
Pan-cancer and single-cell analysis reveal dual roles of lymphocyte activation gene-3 (LAG3) in cancer immunity and prognosis
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-024-74808-4. Article type: Research Article Keywords: LAG3, Immune checkpoint,…
Pan-cancer analysis of Sp1 with a focus on immunomodulatory roles in gastric cancer
Abstract Background: Sp1, a transcription factor, regulates essential cellular processes and plays important tumorigenic roles across diverse cancers. However, comprehensive…
The prognostic value and immunological role of calcium/calmodulin dependent protein kinase kinase 2 (CAMKK2) in pan-cancer study
Abstract A thorough assessment of calcium/calmodulin dependent protein kinase kinase 2 (CAMKK2) in pan-cancer studies is currently absent. We integrate…
Unveiling the pan-cancer landscape of S100A16: A comprehensive analysis of prognostic significance, drug sensitivity, and immunomodulatory roles
Abstract Accumulating evidence supports the notion that S100A16 exhibits differential expression in many human cancers, affecting cellular functions associated with…
EBNA1BP2 identified as potential prognostic biomarker for multiple tumor types in pan-cancer analysis
Abstract Background: Epstein-Barr virus (EBV) infection has been closely linked to the development of various types of cancer. EB nuclear…
Exploring MPC1 as a potential ferroptosis-linked biomarker in the cervical cancer tumor microenvironment: a comprehensive analysis
Abstract Background: The increasing problems of drug and radiotherapy resistance in cervical cancer underscores the need for novel methods for…