Cuproptosis: molecular mechanisms, cancer prognosis, and therapeutic applications
Abstract Cuproptosis differs from other forms of cell death, such as apoptosis, necroptosis, and ferroptosis, in its unique molecular mechanisms…
Cancer prognosis
In‐Depth Examination of TPBG as a New Predictive Indicator for Gastric Cancer
Abstract Trophoblast glycoprotein (TPBG) plays a significant part in the growth of specific cancers, yet its connection to gastric cancer…
The expression landscape and clinical significance of methyltransferase-like 17 in human cancer and hepatocellular carcinoma: a pan-cancer analysis using multiple databases
Abstract Background: Methyltransferase-like (METTL) family protein plays a crucial role in the progression of malignancies. However, the function of METTL17…
Pan-cancer analysis and single-cell analysis identifies the CENPN as a biomarker for survival prognosis and immunotherapy
Abstract Background: Centromere protein N (CENPN), located on chromosome 16q23.2, encodes vital nucleosome-associated complexes that are essential for dynamic assembly…
Identification of SETD4 as an Onco‐Immunological Biomarker Encompassing the Tumor Microenvironment, Prognoses, and Therapeutic Responses in Various Human Cancers
Abstract Background: SET domain‐containing protein 4 (SETD4) is a histone methyltransferase that has been shown to modulate cell proliferation, differentiation,…
Comprehensive analysis of the prognostic, immunological, and diagnostic roles of SIRT1 in pan-cancer and its validation in KIRC
Abstract Background: Disturbances in DNA damage repair may lead to cancer. SIRT1, an NAD+-dependent deacetylase, plays a crucial role in…
Multiomic characterization, immunological and prognostic potential of SMAD3 in pan-cancer and validation in LIHC
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-024-84553-3. Article type: Research Article Keywords: smad3, Pan-cancer, TGF-β,…
Identification of hub genes and potential molecular mechanisms related to radiotherapy in thyroid cancer
Abstract Radiotherapy is a common approach during the treatment of thyroid cancer (THCA). It is urgent to identify the radiotherapy-related…
Multiomics analysis reveals the involvement of NET1 in tumour immune regulation and malignant progression
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-024-83714-8. Article type: Research Article Keywords: NET1, Pan-cancer, Prognosis,…
The expression of CCL17 and potential prognostic value on tumor immunity in thyroid carcinoma based on bioinformatics analysis
Abstract Although CCL17 has been reported to exert a vital role in many cancers, the related studies in the thyroid…