Abstract Rationale: Cancer of unknown primary (CUP) is a group of rare malignancies with poor prognosis and unidentifiable tissue-of-origin. Distinct…
Abstract The metastatic cancer of unknown primary (CUP) sites remains a leading cause of cancer death with few therapeutic options.…
Abstract Background: Cancer of unknown primary (CUP), representing approximately 3-5% of all malignancies, is defined as metastatic cancer where a…
Abstract Sequencing-based identification of tumor tissue-of-origin (TOO) is critical for patients with cancer of unknown primary lesions. Even if the…