Hypoxia Promotes Syndecan-3 Expression in the Tumor Microenvironment
Abstract The syndecan (Sdc) family is comprised of four members of cell surface molecules (Sdc-1 to 4) with different biological…
cancer immunotherapy
Comprehensive Analysis of the Expressionand Prognosis for TDO2 in Breast Cancer
Abstract A plethora of previous studies have been focused on the role of indoleamine 2,3-dioxygenase 1 (IDO1) in cancer immunity;…
The Highs and Lows of Cannabis in Cancer Treatment and Bone Marrow Transplantation
Abstract In the last decade, we have observed an increased public and scientific interest in the clinical applications of medical…
Long-term benefit from immune modulation and anti-inflammatory treatment in metastatic mesothelioma
Abstract A 64 year old male heating engineer was investigated for a persistent cough and found to have epithelioid mesothelioma…
Correlate tumor mutation burden with immune signatures in human cancers
Abstract Background: Tumor mutation burden (TMB) has been associated with cancer immunotherapeutic response and cancer prognosis. Although many explorations have…
The Expression and Prognostic Impact of Immune Cytolytic Activity-Related Markers in Human Malignancies: A Comprehensive Meta-analysis
Abstract Background: Recently, immune-checkpoint blockade has shown striking clinical results in different cancer patients. However, a significant inter-individual and inter-tumor…