Prognostic value of mitochondrial CKMT2 in Pan-cancer and its tumor immune correlation analysis
Abstract Mitochondrial metabolism has been shown to play a key role in immune cell survival and function, but mitochondrial creatine…
cancer immunology
Comprehensive pan‑cancer analysis of potassium voltage-gated channel Q4 (KCNQ4) gene across multiple human malignant tumors
Abstract A large number of studies indicate that Potassium Voltage-Gated Channel Q4 (KCNQ4) gene is the cause of non-syndromic hearing…
Establishment of a novel indicator of pyroptosis regulated gene transcription level and its application in pan-cancer
Abstract Pyroptosis is a type of programmed cell death and plays a dual role in distinct cancers. It is elusive…
Gene S-phase kinase associated protein 2 is a novel prognostic marker in human neoplasms
Abstract Background: Neoplasms are a series of diseases affecting human health. Prognostic and tumor status–related markers for various tumors should…
Prognostic and immunological role of FDX1 in pan-cancer: an in-silico analysis
Abstract Previous research has demonstrated that ferredoxin 1 (FDX1) contributes to the accumulation of toxic lipoylated dihydrolipoamide S-acetyltransferase (DLAT) and…
High expression of RNF31 is associated with tumor immune cell infiltration and leads to poor prognosis in liver hepatocellular carcinoma
Abstract Ring finger protein 31 (RNF31) has been found to play an important role in tumor immunity. However, the role…
Multi-omics pan-cancer study of cuproptosis core gene FDX1 and its role in kidney renal clear cell carcinoma
Abstract Background: The mechanism of copper-induced cellular death was newly discovered and termed cuproptosis. Inducing cuproptosis in cancer cells is…
A pan-cancer analysis of the FAT1 in human tumors
Abstract FAT atypical cadherin 1 (FAT1) is one of the most mutagenic genes in tumors, and several critical studies have…
Pan-cancer analysis of the prognostic and immunological role of PAQR4
Abstract Progestin and adipoQ receptor family member 4 (PAQR4) is a protein-coding gene. Recent studies have shown that PAQR4 is…
The Inflammasomes Adaptor Protein PYCARD Is a Potential Pyroptosis Biomarker Related to Immune Response and Prognosis in Clear Cell Renal Cell Carcinoma
Abstract Simple Summary: Inflammation has been recognized as one of the hallmarks of cancers. PYCARD, the adaptor protein of inflammasomes,…