The endocannabinoid system in cancer biology: a mini-review of mechanisms and therapeutic potential
Abstract The Endocannabinoid System (ECS) plays a critical role in maintaining physiological homeostasis, influencing a range of processes such as…
cancer biology
Pan-cancer analysis reveals immunological and prognostic significance of CCT5 in human tumors
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-88339-z. Article type: Research Article Keywords: Cancer biology, Human…
iSubGen generates integrative disease subtypes by pairwise similarity assessment
Abstract There are myriad types of biomedical data—molecular, clinical images, and others. When a group of patients with the same…
Gene S-phase kinase associated protein 2 is a novel prognostic marker in human neoplasms
Abstract Background: Neoplasms are a series of diseases affecting human health. Prognostic and tumor status–related markers for various tumors should…
CEP55: an immune-related predictive and prognostic molecular biomarker for multiple cancers
Abstract Background: Centrosomal protein 55 (CEP55) plays a significant role in specific cancers. However, comprehensive research on CEP55 is lacking…
PrognosiT: Pathway/gene set-based tumour volume prediction using multiple kernel learning
Abstract Background: Identification of molecular mechanisms that determine tumour progression in cancer patients is a prerequisite for developing new disease…
Modulating FOXO3 transcriptional activity by small, DBD-binding molecules
Abstract FOXO transcription factors are critical regulators of cell homeostasis and steer cell death, differentiation and longevity in mammalian cells.…
Dysregulation, functional implications, and prognostic ability of the circadian clock across cancers
Abstract It has been proposed that the circadian rhythm generally plays important roles in tumor suppression, but there is also…