Pancreatic Cancer and Cachexia—Metabolic Mechanisms and Novel Insights
Abstract Cachexia is a major characteristic of multiple non-malignant diseases, advanced and metastatic cancers and it is highly prevalent in…
cachexia
New Prospect for Cancer Cachexia: Medical Cannabinoid
Abstract Cachexia is a common term for the wasting symptoms which may appear in almost every chronic illness, such as…
Dronabinol oral solution in the management of anorexia and weight loss in AIDS and cancer
Abstract The true incidence of anorexia secondary to human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) and cancer is not well…
Megestrol acetate for cachexia–anorexia syndrome. A systematic review
Abstract In 1993, megestrol acetate (MA) was approved by the US Food and Drug Administration for the treatment of anorexia,…
Study Design and Rationale for the Phase 3 Clinical Development Program of Enobosarm, a Selective Androgen Receptor Modulator, for the Prevention and Treatment of Muscle Wasting in Cancer Patients (POWER Trials)
Abstract Muscle wasting in cancer is a common and often occult condition that can occur prior to overt signs of…
Clinical utility of dronabinol in the treatment of weight loss associated with HIV and AIDS
Abstract Since the beginning of the HIV/AIDS epidemic, weight loss has been a common complaint for patients. The use of…
Pancreatic cancer cachexia: a review of mechanisms and therapeutics
Abstract Over the last decade, we have gained new insight into the pathophysiology of cachexia associated with pancreatic cancer. Unfortunately,…
Cancer cachexia—pathophysiology and management
Abstract About half of all cancer patients show a syndrome of cachexia, characterized by anorexia and loss of adipose tissue…