CD58 reshapes the immunosuppressive microenvironment in gliomas through PD-L1 upregulation
Abstract Background: Cluster of Differentiation 58 (CD58), a critical immune regulator, is implicated in tumor immune evasion, yet its role…
Abstract Background: Cluster of Differentiation 58 (CD58), a critical immune regulator, is implicated in tumor immune evasion, yet its role…
Abstract Chemokine ligand 11 is a member of the CXC chemokine family and exerts its biological function mainly through binding…
Abstract Target identification is a crucial process in drug development, aiming to identify key proteins, genes, and signal pathways involved…
Abstract Human endogenous retroviruses represent approximately 8% of our genome. Most of these sequences are defective except for a few…
Abstract Electronic supplementary material: The online version of this article (10.1186/s13578-018-0266-7) contains supplementary material, which is available to authorized users.…