Evaluating the Potential of PSMA Targeting in CNS Tumors: Insights from Large-Scale Transcriptome Profiling
Abstract Prostate-specific membrane antigen (PSMA) is widely used in prostate cancer imaging and therapy, and there is growing interest in…
brain tumors
Cancer biotherapy: review and prospect
Abstract Malignant tumors pose a grave threat to the quality of human life. The prevalence of malignant tumors in China…
A Strategy Utilizing Protein–Protein Interaction Hubs for the Treatment of Cancer Diseases
Abstract We describe a strategy for the development of a rational approach of neoplastic disease therapy based on the demonstration…
Cannabinoids to Improve Health-Related Quality of Life in Patients with Neurological or Oncological Disease: A Meta-Analysis
Abstract Background: Cannabinoids have been suggested to alleviate frequently experienced symptoms of reduced mental well-being such as anxiety and depression.…
Targeting the Sphingolipid Rheostat in Gliomas
Abstract Gliomas are highly aggressive cancer types that are in urgent need of novel drugs and targeted therapies. Treatment protocols…
Metastatic primary brain rhabdomyosarcoma in a pediatric patient: illustrative case
Abstract BACKGROUND: Primary intracranial rhabdomyosarcoma is an extraordinarily rare malignant tumor, with even fewer presenting with distant metastasis. To date,…
THC Reduces Ki67-Immunoreactive Cells Derived from Human Primary Glioblastoma in a GPR55-Dependent Manner
Abstract Simple Summary: Glioblastoma (GBM) is the most frequent primary brain tumor entity with poor prognosis and resistance to current…
Membrane Transporters for Amino Acids as Players of Cancer Metabolic Rewiring
Abstract Cancer cells perform a metabolic rewiring to sustain an increased growth rate and compensate for the redox stress caused…
Cannabis Therapeutics and the Future of Neurology
Abstract Neurological therapeutics have been hampered by its inability to advance beyond symptomatic treatment of neurodegenerative disorders into the realm…