Abstract Rationale: Anecdotally, both acute and chronic cannabis use have been associated with apathy, amotivation, and other reward processing deficits.…
Abstract Although there is emergent evidence illustrating neural sensitivity to cannabis cues in cannabis users, the specificity of this effect…
Abstract Introduction: Decades of research have demonstrated the importance of social influence in initiation and maintenance of drug use, but…
Abstract The therapeutic properties of cannabinoids have been well demonstrated but are overshadowed by such adverse effects as cognitive and…
Abstract Background: The cannabinoid cannabinoid type 1 (CB1) neutral antagonist tetrahydrocannabivarin (THCv) has been suggested as a possible treatment for…
Abstract Background: Disturbances in the regulation of reward and aversion in the brain may underlie disorders such as obesity and…
Abstract 2-Arachidonoylglycerol (2-AG) is the most potent endogenous ligand of brain cannabinoid CB1 receptors and is synthesized on demand from…
Abstract Over the last decades, the endocannabinoid system has been implicated in a large variety of functions, including a crucial…
Abstract Recent evidence has implicated the endocannabinoid (eCB) system in nicotine addiction. The eCB system also has an important role…
Abstract Rationale: Disturbed reward processing in humans has been associated with a number of disorders, such as depression, addiction, and…