Endocannabinoid signaling in glioma
Abstract High‐grade gliomas constitute the most frequent and aggressive form of primary brain cancer in adults. These tumors express cannabinoid…
brain lower grade glioma
Cannabis Biomolecule Effects on Cancer Cells and Cancer Stem Cells: Cytotoxic, Anti-Proliferative, and Anti-Migratory Activities
Abstract Cancer is a complex family of diseases affecting millions of people worldwide. Gliomas are primary brain tumors that account…
Pan-cancer analysis reveals NUP37 as a prognostic biomarker correlated with the immunosuppressive microenvironment in glioma
Abstract Nucleoporin 37 kDa (NUP37), a member of the nucleoporin family, has been reported to regulate the proliferation and apoptosis…
Violations of proportional hazard assumption in Cox regression model of transcriptomic data in TCGA pan-cancer cohorts
Keywords: CPH, Cox proportional hazard regression, PH, proportional hazard, TCGA, The Cancer Genome Atlas, OS, overall survival, GEO, Gene Expression…
Identification of Methylation Immune Subtypes and Establishment of a Prognostic Signature for Gliomas Using Immune-Related Genes
Abstract DNA methylation patterns are essential in understanding carcinogenesis. However, the relationship between DNA methylation and the immune process has…
IFI30 as a prognostic biomarker and correlation with immune infiltrates in glioma
Abstract Background: Increased evidence indicates that the tumour microenvironment (TME) plays an essential role in the development, treatment and prognosis…
Cannabidiol Induces Apoptosis and Perturbs Mitochondrial Function in Human and Canine Glioma Cells
Abstract Cannabidiol (CBD), the major non-psychoactive compound found in cannabis, is frequently used both as a nutraceutical and therapeutic. Despite…
METTL7B is a novel prognostic biomarker of lower-grade glioma based on pan-cancer analysis
Abstract Methyltransferase-like 7B (METTL7B) is a member of the methyltransferase-like protein family that plays an important role in the development…
Fibroblast Growth Factor Signalling in the Diseased Nervous System
Abstract Fibroblast growth factors (FGFs) act as key signalling molecules in brain development, maintenance, and repair. They influence the intricate…
A pan-cancer analysis of HER2 index revealed transcriptional pattern for precise selection of HER2-targeted therapy
Abstract Background: The prevalence of HER2 alterations in pan-cancer indicates a broader range of application of HER2-targeted therapies; however, biomarkers…