The prognostic and immune significance of PLBD1 in pan-cancer and its roles in proliferation and invasion of glioma
Abstract Cancer is a destructive disease and is currently the leading cause of major threats to human health. PLBD1 is…
brain lower grade glioma
MRPS23 is a novel prognostic biomarker and promotes glioma progression
Abstract Mitochondrial ribosomal protein S23 (MRPS23), a component of the ribosome small subunit, has been reported to be overexpressed in…
IL4I1 in M2-like macrophage promotes glioma progression and is a promising target for immunotherapy
Abstract Background: Glioma is the prevailing malignant intracranial tumor, characterized by an abundance of macrophages. Specifically, the infiltrating macrophages often…
A comprehensive and systematic analysis of Dihydrolipoamide S-acetyltransferase (DLAT) as a novel prognostic biomarker in pan-cancer and glioma
Abstract Background: Dihydrolipoamide S-acetyltransferase (DLAT) is a subunit of the pyruvate dehydrogenase complex (PDC), a rate-limiting enzyme complex, that can…
CCDC103 as a Prognostic Biomarker Correlated with Tumor Progression and Immune Infiltration in Glioma
Abstract Background: The Coiled-coil domain-containing proteins (CCDCs) are expressed in many cancers, but the role of Coiled-coil domain-containing protein 103…
Nuclear mitochondria-related genes-based molecular classification and prognostic signature reveal immune landscape, somatic mutation, and prognosis for glioma
Abstract Background: Glioma is the most frequent malignant primary brain tumor, and mitochondria may influence the progression of glioma. The…
Clusterin Is a Prognostic Biomarker of Lower-Grade Gliomas and Is Associated with Immune Cell Infiltration
Abstract Dysregulation of clusterin (CLU) has been demonstrated in many cancers and has been proposed as a regulator of carcinogenesis.…
Systematic analysis of the necroptosis index in pan-cancer and classification in discriminating the prognosis and immunotherapy responses of 1716 glioma patients
Abstract Necroptosis is a programmed form of necrotic cell death that serves as a host gatekeeper for defense against invasion…
A potential immunotherapeutic and prognostic biomarker for multiple tumors including glioma: SHOX2
Abstract Background: Short stature homeobox 2 (SHOX2) is significant gene in the development and progression of multiple types of tumors.…
High expression of six-transmembrane epithelial antigen of prostate 3 promotes the migration and invasion and predicts unfavorable prognosis in glioma
Abstract Recent studies have suggested that ferroptosis, a form of iron-dependent regulated cell death, might play essential roles in tumor…