Metastatic primary brain rhabdomyosarcoma in a pediatric patient: illustrative case
Abstract BACKGROUND: Primary intracranial rhabdomyosarcoma is an extraordinarily rare malignant tumor, with even fewer presenting with distant metastasis. To date,…
bone metastasis
Colorectal Cancer Stem Cells Fuse with Monocytes to Form Tumour Hybrid Cells with the Ability to Migrate and Evade the Immune System
Abstract Simple Summary: Colorectal cancer survival rates strongly decrease from initial to more advanced stages, primarily because of the occurrence…
The close interaction between hypoxia-related proteins and metastasis in pancarcinomas
Abstract Many primary-tumor subregions exhibit low levels of molecular oxygen and restricted access to nutrients due to poor vascularization in…
Identification of DPP4/CTNNB1/MET as a Theranostic Signature of Thyroid Cancer and Evaluation of the Therapeutic Potential of Sitagliptin
Abstract Simple Summary: In recent years, the incidence of thyroid cancer has been increasing globally, with papillary thyroid cancer (PTCa)…
MicroRNA-200c-3p Negatively Regulates ATP2A2 and Promotes the Progression of Papillary Thyroid Carcinoma
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s10528-022-10184-w. Article type: Research Article Keywords: microRNA, Papillary thyroid…
Pan-Cancer DNA Methylation Analysis and Tumor Origin Identification of Carcinoma of Unknown Primary Site Based on Multi-Omics
Abstract The metastatic cancer of unknown primary (CUP) sites remains a leading cause of cancer death with few therapeutic options.…
Comprehensive Analysis of the Potential Immune-Related Biomarker Transporter Associated With Antigen Processing 1 That Inhibits Metastasis and Invasion of Ovarian Cancer Cells
Abstract Transporter associated with antigen processing 1 (TAP1) is a protein related immune regulation and plays a role in several…
15-Lipoxygenase and its metabolites in the pathogenesis of breast cancer: A double-edged sword
Abstract 15-lipoxygenase is one of the key enzymes for the metabolism of unsaturated fatty acids that its manipulation has been…
The Endocannabinoid System as a Pharmacological Target for New Cancer Therapies
Abstract Simple Summary: Cannabinoids have been shown to suppress tumour cell proliferation, tumour invasion, metastasis, angiogenesis, chemoresistance and epithelial-mesenchymal transition…
Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles
Abstract Simple Summary: Cancer metastasis is considered to be one of the most significant causes of cancer morbidity, accounting for…