Abstract Background: Cerebral ischemia–reperfusion (I/R) injury is a major consequence of ischemic stroke, leading to blood–brain barrier (BBB) disruption, neuroinflammation,…
Abstract Background and objective: Delivering therapeutic drugs to the brain for neurological disorders remains challenging due to the restrictive nature…
Abstract Graphical Abstract: Article type: Review Article Keywords: Stroke, Inflammation, Cannabinoids, Neuroinflammation, Neuroprotection, Astrocytes, Microglia, Blood–Brain Barrier Authors: Eman A.…
Abstract Glioma is the most common malignant tumor in central nervous system, with significant health burdens to patients. Due to…
Abstract Ion channels provide the basis for the nervous system’s intrinsic electrical activity. Neuronal excitability is a characteristic property of…
Abstract Plant-derived phytochemicals have gifted humans with vast therapeutic potentials. Yet, the unique features of the blood–brain barrier significantly limit…
Abstract Background and Objectives: Preclinical studies have shown cannabidiol is protective in models of ischemic stroke. Based on results from…
Abstract Potential therapeutic actions of the cannabinoids delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) are based on their activity as analgesics, anti-emetics,…