Chemical Composition of Commercial Cannabis
Abstract Cannabis is widely used for medicinal and recreational purposes. As a result, there is increased interest in its chemical…
biosynthetic metabolomics pathways
Transcriptomic and metabolomic analyses reveal the differential accumulation of phenylpropanoids and terpenoids in hemp autotetraploid and its diploid progenitor
Abstract Background: Cannabis sativa, a dioecious plant that has been cultivated worldwide for thousands of years, is known for its…
A machine learning approach for understanding the metabolomics response of children with autism spectrum disorder to medical cannabis treatment
Abstract Autism spectrum disorder (ASD) is a neurodevelopmental condition impacting behavior, communication, social interaction and learning abilities. Medical cannabis (MC)…
Stable Isotope Ratio Analysis for Authentication of Natural Antioxidant Cannabidiol (CBD) from Cannabis sativa
Abstract Cannabidiol (CBD) is a non-psychoactive cannabinoid of Cannabis sativa that exhibits several beneficial pharmacological effects, including anti-inflammatory and antioxidant…
Cannabis-Responsive Biomarkers: A Pharmacometabolomics-Based Application to Evaluate the Impact of Medical Cannabis Treatment on Children with Autism Spectrum Disorder
Abstract Introduction: Autism spectrum disorder (ASD) is a group of neurodevelopmental conditions that impact behavior, communication, social interaction, and learning…
Beneficial metabolic transformations and prebiotic potential of hemp bran and its alcalase hydrolysate, after colonic fermentation in a gut model
Abstract Hemp seed bran (HB) is an industrial food byproduct that is generally discarded. Knowledge on the functional capabilities of…
In the Swim of Cannabis: Developmental Toxicity and Metabolomic Pathway Alterations of Zebrafish Larvae Exposed to THC for the Assessment of Its Potential Environmental and Human Health Impact
Abstract As the pharmacological properties and therapeutic applications of Cannabis sativa L. pace with the upsurge of interest of the…
Multiomic Analysis Reveals Disruption of Cholesterol Homeostasis by Cannabidiol in Human Cell Lines
Abstract The nonpsychoactive cannabinoid, cannabidiol (CBD), is Food and Dug Administration approved for treatment of two drug-resistant epileptic disorders and…
Beyond Δ9-tetrahydrocannabinol and cannabidiol: chemical differentiation of cannabis varieties applying targeted and untargeted analysis
Abstract Graphical abstract: Supplementary Information: The online version contains supplementary material available at 10.1007/s00216-022-04026-2. Article type: Research Article Keywords: Principal…
Mechanisms Underlying Synergistic Killing of Polymyxin B in Combination with Cannabidiol against Acinetobacter baumannii: A Metabolomic Study
Abstract Polymyxins have resurged as the last-resort antibiotics against multidrug-resistant Acinetobacter baumannii. As reports of polymyxin resistance in A. baumannii…