Uncovering the antiinflammatory potential of Lactiplantibacillus Plantarum fermented Cannabis Sativa L seeds
Abstract Inflammation acts as a dual role in disease initiation and progression, while Cannabis sativa L. (hemp) seeds, known for…
biosynthetic metabolomics pathways
Longitudinal metabolomics of human plasma reveal metabolic dynamics and predictive markers of antituberculosis drug-induced liver injury
Abstract Supplementary Information: The online version contains supplementary material available at 10.1186/s12931-024-02837-8. Article type: Research Article Keywords: Tuberculosis, Drug-induced liver…
Comparative profiling of serum, urine, and feces bile acids in humans, rats, and mice
Abstract Bile acids (BAs) play important pathophysiological roles in both humans and mammalian animals. Laboratory rats and mice are widely…
Integrating fecal metabolomics and intestinal microbiota to study the mechanism of cannabidiol in the treatment of idiopathic pulmonary fibrosis
Abstract Introduction: Idiopathic pulmonary fibrosis is a chronic interstitial lung disease characterized by excessive deposition of extracellular matrix. Cannabidiol, a…
Chemical Composition of Commercial Cannabis
Abstract Cannabis is widely used for medicinal and recreational purposes. As a result, there is increased interest in its chemical…
Transcriptomic and metabolomic analyses reveal the differential accumulation of phenylpropanoids and terpenoids in hemp autotetraploid and its diploid progenitor
Abstract Background: Cannabis sativa, a dioecious plant that has been cultivated worldwide for thousands of years, is known for its…
A machine learning approach for understanding the metabolomics response of children with autism spectrum disorder to medical cannabis treatment
Abstract Autism spectrum disorder (ASD) is a neurodevelopmental condition impacting behavior, communication, social interaction and learning abilities. Medical cannabis (MC)…
Stable Isotope Ratio Analysis for Authentication of Natural Antioxidant Cannabidiol (CBD) from Cannabis sativa
Abstract Cannabidiol (CBD) is a non-psychoactive cannabinoid of Cannabis sativa that exhibits several beneficial pharmacological effects, including anti-inflammatory and antioxidant…
Systematic analysis of the aberrances and functional implications of cuproptosis in cancer
Abstract Cuproptosis is a novel form of cell death driven by a copper-dependent proteotoxic stress response whose comprehensive landscape in…
Cannabis-Responsive Biomarkers: A Pharmacometabolomics-Based Application to Evaluate the Impact of Medical Cannabis Treatment on Children with Autism Spectrum Disorder
Abstract Introduction: Autism spectrum disorder (ASD) is a group of neurodevelopmental conditions that impact behavior, communication, social interaction, and learning…