Identification of species-specific peptide markers in cold-pressed oils
Abstract In recent years, cold-pressed vegetable oils have become very popular on the global market. Therefore, new versatile methods with…
biomarkers
Links between central CB1-receptor availability and peripheral endocannabinoids in patients with first episode psychosis
Abstract There is an established, link between psychosis and metabolic abnormalities, such as altered glucose metabolism and dyslipidemia, which often…
mGlu5 receptor availability in youth at risk for addictions: effects of vulnerability traits and cannabis use
Abstract The excitatory neurotransmitter glutamate has been implicated in experience-dependent neuroplasticity and drug-seeking behaviors. Type 5 metabotropic glutamate (mGlu5) receptors…
Cigarette and Cannabis Smoking Effects on GPR15+ Helper T Cell Levels in Peripheral Blood: Relationships with Epigenetic Biomarkers
Abstract Background: Smoking causes widespread epigenetic changes that have been linked with an increased risk of smoking-associated diseases and elevated…
The Interplay between the Endocannabinoid System, Epilepsy and Cannabinoids
Abstract Epilepsy is a neurological disorder that affects approximately 50 million people worldwide. There is currently no definitive epilepsy cure.…
Highly Predictive Genetic Markers Distinguish Drug-Type from Fiber-Type Cannabis sativa L
Abstract Genetic markers can be used in seeds and in plants to distinguish drug-type from fiber-type Cannabis Sativa L. varieties…
Perspectives on miRNAs as Epigenetic Markers in Osteoporosis and Bone Fracture Risk: A Step Forward in Personalized Diagnosis
Abstract Aging is associated with an increased incidence of age-related bone diseases. Current diagnostics (e.g., conventional radiology, biochemical markers), because…
24S-Hydroxycholesterol Is Associated with Agitation Severity in Patients with Moderate-to-Severe Alzheimer’s Disease: Analyses from a Clinical Trial with Nabilone
Abstract Background: Agitation is a prevalent and difficult-to-treat symptom of Alzheimer’s disease (AD). The endocannabinoid system (ECS) has been a…
Are innovation and new technologies in precision medicine paving a new era in patients centric care?
Abstract Healthcare is undergoing a transformation, and it is imperative to leverage new technologies to generate new data and support…
Lower circulating endocannabinoid levels in children with autism spectrum disorder
Abstract Background: The endocannabinoid system (ECS) is a major regulator of synaptic plasticity and neuromodulation. Alterations of the ECS have…