Roles of HMGBs in Prognosis and Immunotherapy: A Pan-Cancer Analysis
Abstract Background: High mobility group box (HMGB) proteins are DNA chaperones involved in transcription, DNA repair, and genome stability. Extracellular…
Biomarker
High DSCC1 Level Predicts Poor Prognosis of Lung Adenocarcinoma
Abstract Purpose: To evaluate the role of DSCC1 in LUAD. Patients and Methods: Based on TCGA and GTEx, the Wilcoxon…
TPD52L2 Is a Prognostic Biomarker and Correlated With Immune Infiltration in Lung Adenocarcinoma
Abstract Tumor protein D52-like 2 (TPD52L2) belongs to the members of the TPD52 family. TPD52L2 was reported to regulate proliferation…
Longitudinal Assessment of Tau-Associated Pathology by 18F-THK5351 PET Imaging: A Histological, Biochemical, and Behavioral Study
Abstract Several common and debilitating neurodegenerative disorders are characterized by the intracellular accumulation of neurofibrillary tangles (NFTs), which are composed…
Identification of prostate cancer specific methylation biomarkers from a multi-cancer analysis
Abstract Background: Detecting prostate cancer at a non-aggressive stage is the main goal of prostate cancer screening. DNA methylation has…
Bioinformatics Analyses Reveal the Prognostic Value and Biological Roles of SEPHS2 in Various Cancers
Abstract Purpose: Selenophosphate synthetase 2 (SEPHS2) has been shown to regulate selenoprotein biosynthesis by catalyzing the synthesis of active selenium…
A Novel Prognostic Biomarker LPAR6 in Hepatocellular Carcinoma via Associating with Immune Infiltrates
Abstract Background and Aims: LPAR6 is the most recently determined G protein-coupled receptor of lysophosphatidic acid, and hardly any study…
A Pan-Cancer Analysis of the Prognostic Value and Expression of Adenylate Cyclase 7 (ADCY7) in Human Tumors
Abstract Background: The role of adenylate cyclase 7 (ADCY7) in cancer is still unclear. This study analyzed the interrelationship between…
CD161, a promising Immune Checkpoint, correlates with Patient Prognosis: A Pan-cancer Analysis
Abstract Background: CD161 is a promising immune checkpoint mainly expressed on natural killer (NK) cells and is essential for immunoregulatory…
Xanthine dehydrogenase as a prognostic biomarker related to tumor immunology in hepatocellular carcinoma
Abstract Background: Xanthine dehydrogenase (XDH) is a critical enzyme involved in the oxidative metabolism of purines, pterin and aldehydes and…