Uniform genomic data analysis in the NCI Genomic Data Commons
Abstract The goal of the National Cancer Institute’s (NCI’s) Genomic Data Commons (GDC) is to provide the cancer research community…
bioinformatics
CD96 Correlates With Immune Infiltration and Impacts Patient Prognosis: A Pan-Cancer Analysis
Abstract Background: Immunotherapy has significantly improved patient outcomes, but encountered obstacles recently. CD96, a novel immune checkpoint expressed on T…
Chemical and Bioinformatics Analyses of the Anti-Leishmanial and Anti-Oxidant Activities of Hemp Essential Oil
Abstract Industrial hemp is a multiuse crop that has been widely cultivated to produce fibers and nutrients. The capability of…
Metabolomic Profile and Antioxidant/Anti-Inflammatory Effects of Industrial Hemp Water Extract in Fibroblasts, Keratinocytes and Isolated Mouse Skin Specimens
Abstract Industrial hemp is a multiuse crop whose phytocomplex includes terpenophenolics and flavonoids. In the present study, the phenolic and…
Multi-Approach Bioinformatics Analysis of Curated Omics Data Provides a Gene Expression Panorama for Multiple Cancer Types
Abstract Studies describing the expression patterns and biomarkers for the tumoral process increase in number every year. The availability of…
Functional genomics of AP-2α and AP-2γ in cancers: in silico study
Abstract Background: Among all causes of death, cancer is the most prevalent and is only outpaced by cardiovascular diseases. Molecular…
Potential Diagnostic and Prognostic Utility of miR-141, miR-181b1, and miR-23b in Breast Cancer
Abstract miRNAs, a group of short noncoding RNAs, are key regulators of fundamental cellular processes and signaling pathways. Dysregulation of…
Exploration of the Potential Biomarkers of Papillary Thyroid Cancer (PTC) Based on RT2 Profiler PCR Arrays and Bioinformatics Analysis
Abstract Background: Papillary thyroid carcinoma (PTC) has increased rapidly over recent years, and radiation, hormone effects, gene mutations, and others…
Identification of Callose Synthases in Stinging Nettle and Analysis of Their Expression in Different Tissues
Abstract Callose is an important biopolymer of β-1,3-linked glucose units involved in different phases of plant development, reproduction and response…
Immune gene signature delineates a subclass of thyroid cancer with unfavorable clinical outcomes
Abstract Thyroid cancer (THCA) is a heterogeneous disease with multiple clinical outcomes Immune cells regulate its progression. Three immunomolecular subtypes…