Pan-cancer atlas analysis of FANCB and its potential mechanism in cholangiocarcinoma
Abstract Cholangiocarcinoma (CHOL) is a tumor with high malignancy and poor prognosis, and its morbidity and mortality have increased significantly…
bioinformatics analysis
Exploring Immune-Related Ferroptosis Genes in Thyroid Cancer: A Comprehensive Analysis
Abstract Background: The increasing incidence and poor outcomes of recurrent thyroid cancer highlight the need for innovative therapies. Ferroptosis, a…
Lipopolysaccharide-binding protein (LBP): a prognostic biomarker for gastric cancer linked to immune infiltration
Abstract Background: Gastric cancer, characterized by rising global incidence and mortality, faces significant challenges due to the lack of effective…
Identification of Novel Gene Signature Predicting Lymph Node Metastasis in Papillary Thyroid Cancer via Bioinformatics Analysis and in vitro Validation
Abstract Background: Although with a good prognosis of papillary thyroid cancer (PTC), patients with PTC and also experiencing lymph node…
Pan-cancer bioinformatics analysis of TIPRL in human tumors
Abstract Introduction: The TOR signaling pathway regulator-like (TIPRL) gene plays a multifaceted role in cancer, yet its pan-cancer profile remains…
Pan‑cancer analysis of oncogene SFXN1 to identify its prognostic and immunological roles in lung adenocarcinoma
Abstract As cancer incidence and mortality rates continue to rise, the urgency for research in this field has increased globally.…
A Comprehensive Pan-Cancer Analysis Reveals GRB7 as a Potential Diagnostic and Prognostic Biomarker
Abstract Background and aim: Growth factor receptor-bound protein 7 (GRB7) belongs to a group of adaptor proteins characterized by their…
Prognostic significance of elevated expression levels of protein phosphatase 1 regulatory subunit 3G in thyroid carcinoma
Abstract The prognosis of the poorly differentiated subtype of thyroid carcinoma (THCA) is less favorable due to its aggressive nature,…
GNA14 may be a potential prognostic biomarker in nasopharyngeal carcinoma
Abstract Background: Nasopharyngeal carcinoma (NPC) is a highly invasive malignant tumor. Recurrence and distant metastasis represent the primary causes of…
Identification of fibrosis-associated biomarkers in heart failure and human cancers
Abstract Background: Heart failure (HF) and cancer share common risk factors and pathophysiological mechanisms, including fibrosis. Identifying biomarkers and therapeutic…