Lack of evidence for the effectiveness or safety of over-the-counter cannabidiol products
Abstract Over the past 5 years, public interest in the potential health benefits of cannabidiol (CBD) has increased exponentially, and…
biochemical safety
Add‐on cannabidiol significantly decreases seizures in 3 patients with SYNGAP1 developmental and epileptic encephalopathy
Abstract Mutations in SYNGAP1 are associated with developmental delay, epilepsy, and autism spectrum disorder (ASD). Epilepsy is often drug‐resistant in…
Characteristics of Older Adults Who Were Early Adopters of Medical Cannabis in the Florida Medical Marijuana Use Registry
Abstract Use of medical marijuana is increasing in the United States and older adults are the fastest growing user group.…
Preliminary Investigation of the Safety of Escalating Cannabinoid Doses in Healthy Dogs
Abstract Objective: To determine the safety and tolerability of escalating doses of three cannabis oil formulations, containing predominantly CBD, THC,…
Recreational cannabis use impairs driving performance in the absence of acute intoxication
Abstract Background: Across the nation, growing numbers of individuals are exploring the use of cannabis for medical or recreational purposes,…
Neurocognition and Subjective Experience Following Acute Doses of the Synthetic Cannabinoid JWH-018: Responders Versus Nonresponders
Abstract Introduction: Synthetic cannabinoid mixtures have been easily accessible for years, leading to the belief that these products were natural…
Adherence to Consolidated Standards of Reporting Trials (CONSORT) Guidelines for Reporting Safety Outcomes in Trials of Cannabinoids for Chronic Pain: Protocol for a Systematic Review
Abstract Background: Chronic pain affects a significant proportion of the population and presents a major challenge to clinicians and pain…
Self-Reported Effectiveness and Safety of Trokie® Lozenges: A Standardized Formulation for the Buccal Delivery of Cannabis Extracts
Abstract Therapeutic use of cannabinoids, the main active ingredients of Cannabis sativa L., is often hindered by their limited bioavailability…
Cannabis for pediatric epilepsy: protocol for a living systematic review
Abstract Background: Pediatric epilepsy, including treatment-resistant forms, has a major effect on the quality of life, morbidity, and mortality of…
Cannabis and intractable chronic pain: an explorative retrospective analysis of Italian cohort of 614 patients
Abstract Background: Despite growing interest in the therapeutic use of cannabis to manage chronic pain, only limited data that address…