Multi-omics analysis and functional validation reveal the oncogenic role of TRIP13
Abstract Background: Thyroid hormone receptor-interacting protein 13 (TRIP13), an enzyme from the AAA-ATPase family, facilitates the assembly or disassembly of…
biochemical recurrence prostate cancer
Association between lifetime co-use of classic psychedelics and cannabis and prostate cancer diagnosis among US adults 50 years and older
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-30172-5. Article type: Research Article Keywords: Classic psychedelic, Cannabis,…
Marijuana Use May Be Associated with Reduced Prevalence of Prostate Cancer: A National Survey on Drug Use and Health Study from United States of America
Abstract Preclinical evidence indicates the potential anti-tumor capabilities of cannabinoids in prostate cancer (PC). We undertook a cross-sectional study using…
A Phase I Dose Escalation and Expansion Study of Epidiolex (Cannabidiol) in Patients with Biochemically Recurrent Prostate Cancer
Abstract Simple Summary: Cannabinoids have been widely used for pain, nausea, and appetite stimulation, and have also shown anti-tumor activity…
Non-Canonical Cannabinoid Receptors with Distinct Binding and Signaling Properties in Prostate and Other Cancer Cell Types Mediate Cell Death
Abstract Cannabinoids exert anti-cancer actions; however, the underlying cytotoxic mechanisms and the cannabinoid receptors (CBRs) involved remain unclear. In this…
Identification of prostate cancer specific methylation biomarkers from a multi-cancer analysis
Abstract Background: Detecting prostate cancer at a non-aggressive stage is the main goal of prostate cancer screening. DNA methylation has…
Treatment with Cannabinoids as a Promising Approach for Impairing Fibroblast Activation and Prostate Cancer Progression
Abstract Endo-, phyto- and synthetic cannabinoids have been proposed as promising anti-cancer agents able to impair cancer cells’ behavior without…
Proapoptotic effect of endocannabinoids in prostate cancer cells
Abstract In the early stages, prostate cancer is androgen- dependent; therefore, medical castration has shown significant results during the initial…