Abstract Monoacylglycerol lipase (MAGL) regulates endocannabinoid 2-arachidonoylglycerol (2-AG) and eicosanoid signalling. MAGL inhibition provides therapeutic opportunities but clinical potential is…
Abstract Cannabis sativa has gained popularity as a “natural substance”, leading many to falsely assume that it is not harmful.…
Abstract Endocannabinoids were implicated in a variety of pathological conditions including anxiety and are considered promising new targets for anxiolytic…
Abstract Cannabidiol (CBD) is on the rise as over-the-counter medication to treat sleep disturbances, anxiety, pain, and epilepsy due to…
Abstract Substance abuse is on the rise, and while many people may use illicit drugs mainly due to their rewarding…
Abstract Psychotropic drugs and transcranial magnetic stimulation (TMS) are effective for treating certain psychiatric conditions. Drugs and TMS have also…
Abstract Cannabis sativa, also known as “hemp” or “weed,” is a versatile plant with various uses in medicine, agriculture, food,…
Abstract The medical use of cannabis has a very long history. Although many substances called cannabinoids are present in cannabis,…
Abstract The potential synergistic effects of combining cannabinoids and opioids for analgesia has received considerable attention. No studies to date…
Abstract The non-euphorigenic phytocannabinoid cannabidiol (CBD) has been used successfully to treat childhood-onset epilepsies. These conditions are associated with developmental…